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研究実績 2017年

原著論文 総説および解説

原著

  1. Kodama, Y., Kishimoto, Y., Muramatsu, Y., Tatebe, J., Yamamoto, Y., Hirota, N., Itoigawa, Y., Atsuta, R., Koike, K., Sato, T., Aizawa, K., Takahashi, K., Morita, T., Homma, S., Seyama, K., Ishigami, A. : Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome, and bronchial asthma. Clin. Repir. J. 11(6), 915–924, November 2017.
  2. Jang B, Ishigami A, Kim YS, Choi EK. : The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells. Int J Mol Sci. 2017 Oct 27;18(11). pii: E2258.
  3. Takahashi K, Ishigami A. : Anti-aging effects of coffee. Aging (Albany NY). 2017 Aug 29;9(8):1863-1864.
  4. Suzuki Y, Sato T, Sugimoto M, Baskoro H, Karasutani K, Mitsui A, Nurwidya F, Arano N, Kodama Y, Hirano SI, Ishigami A, Seyama K, Takahashi K. : Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. Biochem Biophys Res Commun. 2017 Oct 7;492(1):74-81.
  5. Sase T, Arito M, Onodera H, Omoteyama K, Kurokawa MS, Kagami Y, Ishigami A, Tanaka Y, Kato T. : Hypoxia-induced production of peptidylarginine deiminases and citrullinated proteins in malignant glioma cells. Biochem Biophys Res Commun. 2017 Jan 1;482(1):50-56.
  6. Nishijima K, Ohno T, Amano A, Kishimoto Y, Kondo Y, Ishigami A, Tanaka S. : Bone Degeneration and Its Recovery in SMP30/GNL-Knockout Mice. J Nutr Health Aging. 2017;21(5):573-578.
  7. Amano A, Kondo Y, Noda Y, Ohta M, Kawanishi N, Machida S, Mitsuhashi K, Senmaru T, Fukui M, Takaoka O, Mori T, Kitawaki J, Ono M, Saibara T, Obayashi H, Ishigami A. : Abnormal lipid/lipoprotein metabolism and high plasma testosterone levels in male but not female aromatase-knockout mice. Arch Biochem Biophys. 622, 47-58 (2017) Mar 21. pii: S0003-9861(17)30177-7.
  8. Nakabo S, Hashimoto M, Ito S, Furu M, Ito H, Fujii T, Yoshifuji H, Imura Y, Nakashima R, Murakami K, Kuramoto N, Tanaka M, Satoh J, Ishigami A, Morita S, Mimori T, Ohmura K. : Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies. Rheumatology (Oxford). 2017 Jul 1;56(7):1217-1226.
  9. Takahashi K, Yanai S, Shimokado K, Ishigami A. : Coffee consumption in aged mice increases energy production and decreases hepatic mTOR levels. Nutrition. 2017 Jun;38:1-8.
  10. Takigawa M, Masutomi H, Kishimoto Y, Shimazaki Y, Hamano Y, Kondo Y, Arai T, Lee J, Ishii T, Mori Y, Ishigami A. : Time-Dependent Alterations of Vancomycin-Induced Nephrotoxicity in Mice. Biol Pharm Bull. 2017;40(7):975-983.
  11. Takahashi K, Takisawa S, Shimokado K, Kono N, Arai H, Ishigami A. : Age-related changes of vitamin E: α-tocopherol levels in plasma and various tissues of mice and hepatic α-tocopherol transfer protein. Eur J Nutr. 2017 Apr;56(3):1317-1327.
  12. Sato Y, Uchida E, Aoki H, Hanamura T, Nagamine K, Kato H, Koizumi T, Ishigami A. : Acerola (Malpighia emarginata DC.) Juice Intake Suppresses UVB-Induced Skin Pigmentation in SMP30/GNL Knockout Hairless Mice. PLoS One. 2017 Jan 23;12(1):e0170438.
  13. Umeda N, Matsumoto I, Tanaka Y, Kawaguchi H, Ebe H, Kagami Y, Ishigami A, Sumida T. : Anti-cyclic citrullinated glucose-6-phosphate isomerase peptide -7 (CCG-7) antibodies were suppressed by biologics treatment and deposited to citrullinated proteins in CD68-positive cells in the RA synovium. Mod Rheumatol. 2017 Jan 4:1-7.
  14. Kunimura Y, Iwata K, Ishigami A, Ozawa H. : Age-related alterations in hypothalamic kisspeptin, neurokinin B, and dynorphin neurons and in pulsatile LH release in female and male rats. Neurobiol Aging. 2017 Feb;50:30-38.
  15. Masutomi H, Kawashima S, Kondo Y, Uchida Y, Jang B, Choi EK, Kim YS, Shimokado K, Ishigami A. : Induction of peptidylarginine deiminase 2 and 3 by dibutyryl cAMP via cAMP-PKA signaling in human astrocytoma U-251MG cells. J Neurosci Res. 2017 Jul;95(7):1503-1512.

総説および解説

  1. 西島和俊、大野民生、天野晶子、岸本祐樹、近藤嘉高、石神昭人、田中愼 : SMP30/GNLノックアウトマウスにおける骨変性とその修復. ビタミン 91: 652-654 (2017)
  2. 小泉美和子、近藤嘉高、伊坂亜友美、石神昭人、鈴木恵美子 : 不安様行動およびストレス誘発性食欲不振に与えるビタミンCの影響. ビタミン 91: 649-651 (2017)
  3. 石神昭人 : カロリー制限はやはりアカゲザルの健康長寿に効果がある. ビタミン 91: 569-572 (2017)
  4. 石神昭人 : 6健康食品やサプリメント2.2)ビタミンCと老化、健康寿命新ガイドラインエビデンスブック. 67-69 (2017)
  5. 内尾隆正、広瀬義隆、室崎伸二、山本佳弘、石神昭人 : 高用量ビタミンC の摂取は加齢に伴う胸腺の萎縮を抑制して免疫細胞数の維持に寄与する. ビタミン 91: 352-354 (2017)

 

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